Dear NMR Enthusiast,
The 23rd Global NMR Educational Tutorial will be given by Prof. Galia Debelouchina, UC San Diego, USA, on the topic:
“Chemical biology tools for the NMR structural biologist”.
Abstract:
Many of the challenging biological problems that NMR spectroscopists study involve large and complex proteins that are also often post-translationally modified. In this tutorial, I will cover NMR friendly approaches to install post-translational modifications efficiently, to segmentally label proteins, and to install various spectroscopic probes in a selective manner. I will cover tools such as inteins and sortase, unnatural amino acid incorporation, native and expressed protein ligation, and bio-orthogonal chemical approaches for protein labeling. I will discuss the advantages and challenges of these tools and present applications from my own lab and the recent literature.
Speaker’s biography:
2005: BA in Chemistry and Mathematics, Colby College
2011: PhD, MIT (Griffin’s lab)
2012-2017: Postdoc, Princeton University (Muir’s lab)
2018-Present: Asstt. Professor, University of California, San Diego
Webinar details:
Time: Tuesday, March 2, 2021, 11:00 AM Boston or 5:00 PM Paris or 9:30 PM Delhi
New Link: https://epfl.zoom.us/j/81308524368
Best regards,
Global NMR Discussion Meetings
Youtube: https://www.youtube.com/c/GlobalNMRDiscussionMeetings/videos
[Organizers:
Adrian Draney (Creighton University Chemistry)
Amrit Venkatesh (Lyndon Emsley Lab, EPFL)
Asif Equbal (Songi Han Lab, UCSB)
Blake Wilson (Robert Tycko Lab, NIH)
Michael Hope (Lyndon Emsley Lab, EPFL)
Mohamed Sabba (Malcolm Levitt Lab, UK)
Mouzhe Xie (Maurer Lab, Uni. Chicago)
PinelopiMoutzouri (Lyndon Emsley Lab, EPFL) ]
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