Dear Colleagues,
A PhD position funded by the ERC is available working in our team (hmrlab.eu) at the Very High Fields NMR Center (CRMN) in the city of Lyon, France.
Facilities. The Center for Very High Field NMR is one of the world’s leading magnetic resonance laboratories, located in the great city of Lyon, which is affiliated to the Lyon-1 University, the CNRS (French National Center for Scientific Research) and the Ecole Normale Supérieure de Lyon. The center is equipped with state-of-the-art NMR spectrometers (500 - 700 - 800 MHz, and the world’s first 1 GHz spectrometer) with two state-of-the-art hyperpolarization machines.
Project Description. In our team we are pioneers in the development of new instrumentation and methods for hyperpolarized magnetic resonance. In particular we develop a method called dissolution dynamic nuclear polarization that allows one to boost the sensitivity by more than 10’000 fold. With this new project called HypFlow we will further develop the method to make it replenishable and therefore highly compatible with a large number of applications in spectroscopy, chemistry, biochemistry or imaging and cancer research. The candidate will in particular work on the development of a new low field hyperpolarizer instrument.
Team-work and perspectives. At the CRMN, you will benefit from unique trainings in magnetic resonance and hyperpolarization (theory and methods, probe construction, cryogenics, etc.), skills of increasing importance in the industrial and academic community. You will have dedicated funding for summer schools, travels, conference attendance. You will have access to state-of-the-art machines, with lots of associated accessories and substantial funding for purchasing any required additional equipment. You will be involved in already fruitful projects, and will evolve in a friendly and very collaborative atmosphere, in which we are promoting healthy work-life balance.
Profile. We are looking for highly motivated candidate who enjoys teamwork, holding a Master in Physics or Chemistry, or Engineering. Skills or interest will be appreciated in spectroscopy, analysis, electronics, radio-frequencies, sensors, CAO design, 3D-printing.
Contract. The position is fully funded, and will be open until filled (3-years contract with extensions).
How to apply. You can contact me directly for further information and send your application to contact@hmrlab.eu including a brief letter (explaining background and motivation) and your CV.
S. J. Elliott, M. Ceillier, O. Cala, Q. Stern, S. F. Cousin, and S. Jannin Simple and cost-effective cross-polarization experiments under dissolution-dynamic nuclear polarization conditions with a 3D-printed 1H-13C background-free radiofrequency coil J. Magn. Reson. Open, vol. 10–11, p. 100033, 2022, doi: 10.1016/j.jmro.2022.100033.
T. El Daraï and S. Jannin Sample formulations for dissolution dynamic nuclear polarization Chem. Phys. Rev., vol. 2, no. 4, p. 041308, 2021, doi: 10.1063/5.0047899.
T. El Daraï, S. F. Cousin, Q. Stern, M. Ceillier, J. Kempf, D. Eshchenko, R. Melzi, M. Schnell, L. Gremillard, A. Bornet, J. Milani, B. Vuichoud, O. Cala, D. Montarnal, and S. Jannin Porous functionalized polymers enable generating and transporting hyperpolarized mixtures of metabolites Nat. Commun., vol. 12, no. 1, pp. 1–9, 2021, doi: 10.1038/s41467-021-24279-2.
Q. Stern, S. F. Cousin, F. Mentink-Vigier, A. C. Pinon, S. J. Elliott, O. Cala, and S. Jannin Direct observation of hyperpolarization breaking through the spin diffusion barrier Sci. Adv., vol. 7, no. 18, pp. 1–14, 2021, doi: 10.1126/sciadv.abf5735.
S. J. Elliott, Q. Stern, M. Ceillier, T. El Daraï, S. F. Cousin, O. Cala, S. Jannin, T. El, S. F. Cousin, O. Cala, S. Jannin, P. Berthault, C. Boutin, C. Martineau-corcos, G. Carret, S. J. Elliott, Q. Stern, M. Ceillier, T. El Daraï, S. F. Cousin, O. Cala, and S. Jannin Practical dissolution dynamic nuclear polarization Prog. Nucl. Magn. Reson. Spectrosc., vol. 126–127, pp. 59, Oct. 2021, doi: 10.1016/j.pnmrs.2021.04.002.
Sami Jannin
Professor 1ère classe at the Lyon 1 University
Member of the Institut Universitaire de France (IUF)
Deputy Director Centre de RMN à Très Hauts Champs http://crmn-lyon.fr
5 rue de la Doua
69100 Villeurbanne FRANCE
Team Leader Hyperpolarized Magnetic Resonance Lab http://hmrlab.eu
Head of Lyon 1 University ERC support program
mobile: +33 6 67 90 77 52
office: +33 4 37 42 35 27
We are hosting HYP21
the 6th Hyperpolarization Conference
in Lyon, Sept. 5th-9th 2021
http://hyp-lyon.org
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