Postdoctoral position on MAS DNP of crystallizing solutions #DNPNMR

Published: Wednesday, 28 September 2022 - 10:00 -0400

Author: Thorsten Maly

A CNRS post-doctoral research position funded by the European Research Council (ERC) is available in the NMR DNP group of the Institut de Chimie Radicalaire in Marseille, France.

The overall aim of the project is to exploit the full potential of magic-angle spinning nuclear dynamic polarization (MAS-DNP) for the characterization of the process of formation of polymorphic organic solids.
The main challenge will consist in developing new experimental approaches in solid-state NMR and MAS DNP to maximize the sensitivity of the technique for the study of small-molecule systems undergoing crystallization from solution. To this aim, the candidate will be required to work on the development of new tools to increase the temporal resolution of the analysis of crystallizing solutions and control the selection of polymorphs by NMR DNP.

The research project will focus more specifically on the following aspects:

  1. the development and application of new experimental protocols to trap metastable phases formed during crystallization processes in the bulk and confined media
  2. the development and/or optimization of MAS DNP experiments for the detection and structural characterization of these phases.

Host laboratory & research environment
The project will take place at the Institut de Chimie Radicalaire de Marseille (ICR, UMR 7273, https://icr.univ-amu.fr/en/), within the solid-state DNP NMR research group (www.mollicalab.fr). Located in the south of France in Marseille, the ICR is internationally recognized for its double expertise in i) the development of new DNP approaches for the characterization of organic solids and ii) the synthesis of radical species currently used as the most effective polarizing agents for the analysis of solids via MAS DNP. With the Spectropole analytical facility on-site, ICR has access to a wide range of instruments for materials analysis, and several NMR spectrometers for liquids and solids with magnetic fields ranging between 300 and 600 MHz. In particular, the laboratory is equipped with a state-of-the-art 400 MHz Bruker MAS-DNP spectrometer (gyrotron) as well as with a 400 MHz wide bore NMR spectrometer dedicated to solids with numerous MAS probes up to 60 kHz. The selected candidate will interact on a day-to-day basis with a team of researchers and students as well as with scientists with whom the team has established collaborations, both nationally and internationally.

Qualifications
This offer is open to candidates with a training in physical chemistry, preferably holding a PhD in the field of solid-state NMR. The ideal candidate is expected to be curious, motivated, and with a strong problem-solving mindset, capable of working on an interdisciplinary project. He/she should demonstrate excellent communication skills (both oral and written), notably in English. Knowledge of French is not required.

Application procedure
The expected starting date is between November 2022 and January 2023. The postdoctoral position is funded by the CNRS initially for one year. Salary is commensurate to experience (2743 et 3896 € gross/month). Applications will be considered on a rolling basis. The CNRS is labeled HR Excellence for Research (HRS4R) and promotes the transparency of the recruitment process and equal opportunities.

To apply, upload your CV and motivation letter (providing two references) here: https://emploi.cnrs.fr/Offres/CDD/UMR7273-GIUMOL-019/Default.aspx

For further information, contact Dr Giulia Mollica at: giulia.mollica@univ-amu.fr

Giulia Mollica - Directrice de Recherche CNRS - ICR Institut de Chimie Radicalaire (UMR CNRS 7273)
Aix-Marseille Université - Service 511 - ST JEROME - Avenue Escadrille Normandie Niemen - 13013 Marseille
Tél: +33(0)4 13 94 57 95
Site : http://www.univ-amu.fr - Email : giulia.mollica@univ-amu.fr
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