Fully funded postdoctoral positions are available in the labs of Prof. Thomas Theis at NC State University and of Prof. Matthew Rosen at the Massachusetts General Hospital. The available postdoc positions are ideally suited for candidates with backgrounds in parahydrogen induced hyperpolarization and/or hyperpolarized imaging.
Interested candidates, please send your CV to ttheis@ncsu.edu and matt@rosenlab.org
The positions are available in the NC State hyperpolarization lab: https://theislab.wordpress.ncsu.edu/ and the Low-field MRI and hyperpolarized media Laboratory of the Athinoula A. Martinos Center for Biomedical Imaging: https://www.nmr.mgh.harvard.edu/lab/lfi
The positions are funded by the Department of Energy for the development of Quantum-Enabled Bioimaging and Sensing Approaches for Bioenergy
Current technology designed to non-invasively monitor the metabolic turnover of naturally occurring biomolecules in plants, roots or smaller model systems faces major obstacles. In case of optical techniques, obstacles include optical penetration depth limitations and chemical specificity. In contrast to optical techniques, Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) are well-established non-invasive techniques that easily report on small changes in chemical structure and perform non-invasive imaging. However, NMR, and even more so MRI, are notoriously insensitive, require large samples and high concentrations, therefore the study of low-concentration metabolites remains out of reach. With quantum entangled sources of nuclear spin order, parahydrogen in particular, it is possible to overcome current technological shortcomings and achieve sensitivity gains of up to seven orders of magnitude, which promise tracking of low concentration metabolites and their chemical transformations deep inside soil.
Thomas Theis, PhD
Assistant Professor
North Carolina State University, Departments of Chemistry, Physics and
UNC & NC State Joint Department of Biomedical Engineering
851 Main Campus Drive, Partners III, Room 363D
Raleigh, NC, 27606
510-363-2368
Hyperpolarization Lab
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