Solvent suppression in solid-state DNP NMR using Electronic Mixing-Mediated Annihilation (EMMA) #DNPNMR

Published: Monday, 10 February 2020 - 16:00 UTC

Author:

Ziarelli, Fabio, Pierre Thureau, Stéphane Viel, and Giulia Mollica. “Solvent Suppression in Solid-State DNP NMR Using Electronic Mixing-Mediated Annihilation (EMMA).” Magnetic Resonance in Chemistry, January 23, 2020.

https://doi.org/10.1002/mrc.5001.

We show here that the Electronic Mixing-Mediated Annihilation (EMMA) method, previously reported for the suppression of background signals in solid-state NMR spectra, can be successfully applied to remove the solvent signals observed in the case of NMR spectra obtained with dynamic nuclear polarization (DNP). The methodology presented here is applied to two standard sample-preparation methods for DNP, namely glass forming and incipient wetness impregnation. It is demonstrated that the EMMA method is complementary to the different methods for solvent suppression based on relaxation filters, and that it can be used to preserve the quantitative information that might be present in the pristine spectra.